Ongoing Research

Chromosome 19 Proteomics Consortium

Human Proteome Project (HPP)

The Human Proteome Project (HPP) is an international project organized by the Human Proteome Organization (HUPO) that aims to revolutionize our understanding of the human proteome via a coordinated effort by many research laboratories around the world. It is designed to map the entire human proteome in a systematic effort using currently available and emerging techniques. Completion of this project will enhance understanding of human biology at the cellular level and lay a foundation for development of diagnostic, prognostic, therapeutic, and preventive medical applications.

Chromosome 19 Proteomics Consortium

A team of international experts led by Prof.Gyorgy Marko-Varga are part of the Chromosome 19 Proteomics Consortium working on characterizing the proteome of human Chromosome 19. Based on the currently available data Chromosome 19 has 1,449 protein encoding genes (Ensembl v69, October 2012) of which 535 (36.9%) proteins are either missing or unknown. Clinnovo is the Indian member of this consortium supporting proteome characterization of Chromosome 19 in Diabetes Type 2 and proteome informatics platform development.

Myopia Genetics Study

Myopia Overview

Myopia (short-sightedness) is a common vision abnormality and is classified as low (-3.00 diopters or less), moderate (-3.00 and -5.00 diopters), and high (-5.00 or more). Myopia affects around 7-20% of Indian population, and increases risk of other eye diseases leading to blindness. The causation of Myopia is multi-factorial and is known to involve genetic and environmental factors. Myopia is most often inherited and runs in families.

Myopia Genetics Study

Clinnovo is currently running a multi-centre study involving familial clusters of high myopic subjects (n=1000) and also individuals with very high myopia (n=500). The study is planned to report in Q4 2014 and will give novel insights into genetic changes in myopia patients in India.